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Humoral immune responses in mice following immunization. (A) SARS-CoV-specific total IgG titers in sera. (B) SARS-CoV-specific IgG1 and IgG2a titers in day 49 sera. Purified inactivated SARS-CoV was used in ELISA as the capture antigen. (C) SARS-CoV neutralizing antibody titers in sera. Error bars represent the S.D. of the mean of five mice per group.
