Table 1.
Local alterations in the inoculum region measured 72 h after inoculation with saponin (Sap) and a candidate vaccine composed of Leishmania braziliensis promastigote protein plus saponin plus sand fly salivary gland extract (LBSapSal)
| Group | Animal code | Nodule size (cm) |
||
|---|---|---|---|---|
| T1a | T2b | T3c | ||
| Sap n = 5 | #03 | – | – | – |
| #05 | 2.5 × 1.5 | 4.0 × 4.5 | – | |
| #14 | – | – | – | |
| #20 | – | 2.0 × 3.0 | 2.0 × 2.0 | |
| #27 | – | – | – | |
| LBSapSal n = 5 | #18 | – | – | – |
| #23 | – | – | 1.0 × 1.0 cm | |
| #28 | – | – | – | |
| #31 | 2.3 × 1.8 cm | – | – | |
| #38 | – | – | – | |
a
T1, 72 h after the first dose.
b
T2, 72 h after the second dose.
c
T3, 72 h after the third dose.