Table 1.
Summary of T cell responses in SARS-recovered subjects at 9 or 11 years post-infection, identified from screening by ELISpot and confirmation by ICS. Percentages of T cell responses represent that of CD4+ or CD8+ T cells over total T cell population after in vitro expansion in the presence of SARS peptide mixtures.
| HLA Class I | Years post-SARS infection | Peptide | Amino acid position | Type of T cell response | Percentages of T cell responses after in vitro expansion | ||
|---|---|---|---|---|---|---|---|
| SARS subject 1 | A*2402 B*1502 C*0801 |
A*0206 B*1525 C*0403 |
9 years | S104 S109 N21 M29 |
516–530 541–555 101–115 141–155 |
CD4+ CD4+ CD4+ CD8+ |
3.9% 3.1% 4.7% 1.0% |
| SARS subject 2 | A*1101 B*5502 C*0302 |
A*3303 B*5801 C*0303 |
9 years | N21 | 101–115 | CD4+ | 0.2% |
| SARS subject 3 | A*0201 B*1502 C*0801 |
A*1101 B*4001 C*1502 |
11 years | S217 M29 |
1081–1095 141–155 |
CD4+ CD8+ |
0.3% 0.3% |