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Results of the Annexin V assaya for apoptosis/necrosis detection in MCF-7 cells treated with compound 8m.
| Cell line | Duration of treatment | Compd. | Early Apoptosis/% |
Late Apoptosis/% |
Necrosis/% |
|---|---|---|---|---|---|
| MCF-7 | 24 h | Control | 0 | 4.4 | 0 |
| 8m | 0 | 1.68 | 11.36 | ||
| 48 h | Control | 0 | 10.60 | 0.84 | |
| 8m | 13.4 | 35.3 | 8.76 |
Results are presented as percentages of early apoptotic cells, late apoptotic/primary necrotic cells, and secondary necrotic cells after 24 h and 48 h treatment at 2 × IC50 (0.16 μM).
