Table 6.

Anti-trypanosomal activity of 5-(3-naphthalen-2-yl-5-aryl-4,5-dihydropyrazol-1-yl)-thiazolidine-2,4-dione derivatives (1a, 2b, 2c).

Comp	Trypanosoma B.B.		Trypanosoma B.G.
	IC50, μM	SD	IC50, μM	SD
1a	13.87	0.36	6.66	1.15
2b	5.43	0.09	2.53	0.12
2c	11.26	0.31	6.10	0.43
Pentamidine	0.0032	0.0003	0.0053	0.0009

IC₅₀ value is the mean +/− the standard deviation (SD) of three independent experiments.