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. 2015 Nov 10;34(2):292–295. doi: 10.1016/j.vaccine.2015.10.127

Table 1.

Recombinant measles vaccine-based virus expressing heterologous antigens.

MV vector Insertion site Inserted targets Experimental animals Authors [ref. No.]
Edm. Zagreb P/M SARS-Corona virus Nucleocapsid, Spike CD46+, IFN-receptor- mice Liniger et al. [22]
Berna Moraten P/M HPV L1 CD46+, IFN-receptor- mice Cantarella et al. [23]
P/M, H/L HIV gp140, Gag-pol, CD46+, IFN-receptor- mice Liniger et al. [24]
Edmonston B P/M, H/L Mumps virus, SIV Mumps F, HN, SIV env, etc. CD46+, IFN-receptor- mice Wang et al. [25]
Schwarz P/M SARS Corona virus Spike CD46+, IFN-receptor- mice Escriou et al. [26]
P/M HIV HIV Gag, RT, Nef Cynomolgus macaques Stebbings et al. [27]
P/M West Nile virus Envelope Squirrel monkey Brandler, et al. [28]
P/M Dengue viruses I-IV Envelope + partial M CD46+, IFN-receptor- mice Brandler et al. [29]
P/M, H/L HIV Gag (P/M), Env (H/L) CD46+, IFN-receptor- mice Guerbois et al. [30]
F and H: replaced SIV gp160+MVF cytoplasmic ND Mourez et al. [31]
P/M Chikungunya virus C-E3-E2-6K-E1 CD46+, IFN-receptor- mice Brandler et al. [32]
Edmonston B, Wild N/P Nipah virus G African green monkey Yoneda et al. [33]
Moraten/Schwarz P/M Hepatits C, E1, E2 CD46+, IFN-receptor- mice Reyes-del Valle et al. [34]
Edm. Zagreb P/M RSV, EB virus SV F, EB gp350 Cotton rats, Rhesus Macaques Mok et al. [39]
AIK-C P/M RSV F, G Cotton rats Sawada et al. [40]
AIK-C P/M RSV NP, M2, F Cotton rats Yamaji et al. [41]

MV: measles virus, Edm. Zagreb: Edmonston Zagreb, HIV: human immunodeficiency virus, HPV: human papilloma virus, SIV: simian immunodeficiency virus, RSV: respiratory syncytial virus, EB: Epstein Barr virus, CD46+, IFN-receptor- mice: human CD46 transgenic and interferon receptor knockout mice.