Table 7.
Characteristics of vaccinia from LC16 lineage
| Lister | LC16 | LC16mO | LC16m8 | |
|---|---|---|---|---|
| Ceiling temperature (RK cells) (°C) | >41 | 41 | 41 | 40.5 |
| Plaque size (RK cells) | L | M | M | M |
| Pock size (CAM cells) | L | L | M | S |
| Proliferation ability in each cell type | ||||
| CAM | +++ | +++ | +++ | +++ |
| Vero cells | +++ | +++ | +++ | + |
| RK cells | +++ | +++ | +++ | +++ |
| CEF cells | ++ | ++ | ++ | ++ |
| Central nervous system pathology | ||||
| Proliferation | ||||
| Rabbit | ++ | + | + | ± |
| Monkey | +++ | + | + | + |
| Mouse | + | + | nd | nd |
| Invasion | ||||
| Mouse | +++ | + | – | – |
| Skin proliferation | ||||
| Rabbit | +++ | +++ | ++ | + |
| Human | ++ | +++ | ++ | + |
| Antibody production ability | ||||
| Rabbit | ++ | +++ | +++ | ++ |
| Human | ++ | +++ | +++ | ++ |
nd = not done. Source: Hashizume [18].