Table 2.
Antibody responses to MV and HIV-env 4 and 8 weeks after immunization with active or UV-inactivated viruses.
| Virus | N | Anti-MV titer (ELISA)a |
Anti-HIV titer (ELISA) |
||||||
|---|---|---|---|---|---|---|---|---|---|
| Week 4b |
Week 8c |
Week 4 |
Week 8 |
||||||
| Titer log10 | SD (±) | Titer log10 | SD (±) | Titer log10 | SD (±) | Titer log10 | SD (±) | ||
| MVbvd | 4 | 3.00 | (0.35) | 4.21 | (0.17) | <0.10 | <0.10 | <0.10 | <0.10 |
| MVb2-HIV-e1 | 4 | 3.35 | (0.52) | 4.11 | (0.25) | 2.30 | (0.25) | 3.81 | (0.25) |
| MVb2-HIV-e1e (UV inactivated) | 4 | 0.50 | (1.00) | 0.50 | (1.00) | <0.10 | <0.10 | <0.10 | <0.10 |
| Naivef | 4 | <0.10 | <0.10 | <0.10 | <0.10 | <0.10 | <0.10 | <0.10 | <0.10 |
a
ELISA titers are optical density values measured at 492 nm. OD values are 2.1-fold above the background.
b
Immunization was performed on day 0 and measured at 4 weeks.
c
Boost was performed at 4 weeks after the prime and measured at 8 weeks.
d
Prime and boost were done with homologous viruses by injecting 104 pfu/mouse.
e
Immunization with a single injection of 104 pfu/mouse.
f
Pool of pre-immune sera of animals before immunization.