Table 4.
| Trial no. | Mice no. | Age and BW | Oral IgY ad. time | Morbidity (%) | Mortality (%) | Mortality of ill mice (%) |
|---|---|---|---|---|---|---|
| 7-1 | 25 | 4–5 D | 1 h before | 24(6/25)# | 20(5/25)# | 91(5/6) |
| Control | 26 | 2.5– | 1 h before | 69(18/26) | 62(16/26) | 89(16/18) |
| 7-2 | 16 | 3.0 g | 1 h after | 38(6/16)# | 31(5/16)# | 83(5/6) |
| Control | 22 | 1 h after | 91(20/22) | 77(17/22) | 80(16/20) | |
| Trial (Ave ± Std) | 31.0 ± 9.9# | 25.5 ± 7.8# | 87.0 ± 5.7 | |||
| Control (Ave ± Std) | 80.0 ± 15.6 | 69.5 ± 10.6 | 84.5 ± 6.4 | |||
| 8-1 | 19 | 5–6 D | 1 h before | 10(2/19) | 5(1/19) | 50(1/2) |
| Control | 19 | 3.0– | 1 h before | 32(6/19) | 32(6/19) | 100(6/6) |
| 8-2 | 19 | 3.5 g | 1 h after | 16(3/19) | 11(2/19) | 67(2/3) |
| Control | 19 | 1 h after | 26(5/19) | 21(4/19) | 80(4/5) | |
| Trial (Ave ± Std) | 13.0 ± 4.2 | 8.0 ± 4.2 | 58.5 ± 12.0 | |||
| Control (Ave ± Std) | 29.0 ± 4.2 | 26.5 ± 7.8 | 90.0 ± 14.1 | |||
a
Oral inoculation dose: 3 × 106 pfu/mouse.
b
Orally administrated IgY dose: neutralization titer 512, 100 μl/mouse.
#
Differences in proportions of morbidity and mortality were tested with the use of the X2 statistic (P < 0.05).