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. 2011 Mar 10;46(6):2236–2242. doi: 10.1016/j.ejmech.2011.03.004

Table 3.

Anticonvulsant screening project (ASP): Test 7 results in mice; 6 Hz assay (Dose 100 mg/kg).

Compd. Test Time (h)
0.25 0.5 1.0 2.0 4.0
5h 6Hza 1/4 1/4 0/4 0/4 0/4
TOXb 0/4 0/4 0/4 0/4 0/4



5i 6Hza 3/4 2/4 2/4 0/4 0/4
TOXb 0/4 0/4 0/4 0/4 0/4
a

Qualitative 6 Hz assay (number of animal protected/number of animals tested).

b

Rotorod toxicity (number of animals exhibiting toxicity/number of animals tested) endpoint: unable to maintain balance on rotorod.