Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
Serotonin (5-HT) receptor and transporter binding afnities of amides S40 and S41.
| Compound | Receptor binding affinity (IC50, μM) |
|||||
|---|---|---|---|---|---|---|
| 5-HT1A | 5-HT2A | 5-HT2C | 5-HT6 | 5-HT7 | 5-HT transporter | |
| S40 | 1.2 | >10 | 8.8 | >10 | >10 | >10 |
| S41 | 2.1 | 6.8 | 4.5 | 5.0 | 5.6 | 6.7 |
| TMCA | 7.6 | >10 | 2.5 | >10 | >10 | >10 |
