Table 7.
Viral versus human proteome overlap at the 7-mer level
| Virusa | 1 | 2 | 3b | 4b | 5 | 6 |
|---|---|---|---|---|---|---|
| HBV | 1,586 | 1,589 | 66 | 102 | 93 | 4.1 |
| JCV | 1,523 | 1,599 | 61 | 108 | 101 | 4.0 |
| Human parvovirus B19 | 1,440 | 1,988 | 49 | 120 | 104 | 3.4 |
| HRV-14 | 2,173 | 2,173 | 60 | 118 | 100 | 2.7 |
| HPV-1 | 2,203 | 2,203 | 69 | 139 | 123 | 3.1 |
| SAF-V | 2,283 | 2,283 | 35 | 51 | 51 | 1.5 |
| HPV16 | 2,404 | 2,404 | 102 | 163 | 121 | 4.2 |
| HTLV-I | 2,553 | 2,553 | 143 | 283 | 215 | 5.6 |
| HCV | 3,004 | 3,004 | 129 | 403 | 369 | 4.2 |
| Rubella virus | 3,167 | 3,167 | 171 | 309 | 282 | 5.3 |
| YFV | 3,405 | 3,405 | 96 | 164 | 153 | 2.8 |
| WNV | 3,427 | 3,427 | 96 | 177 | 170 | 2.8 |
| HIV-1 | 3,079 | 3,517 | 96 | 163 | 148 | 3.1 |
| Rabies virus | 3,570 | 3,570 | 132 | 208 | 192 | 3.6 |
| RRV | 3,595 | 3,595 | 119 | 184 | 169 | 3.3 |
| HIV-2 | 3,278 | 3,705 | 121 | 1,347 | 535 | 3.6 |
| hMPV | 4,109 | 4,109 | 123 | 234 | 212 | 2.9 |
| H5N1 | 4,400 | 4,407 | 96 | 147 | 139 | 2.1 |
| HRSV | 4,474 | 4,474 | 106 | 174 | 162 | 2.3 |
| HPIV3 | 4,806 | 4,806 | 126 | 193 | 170 | 2.6 |
| Lake Victoria marburgvirus | 4,804 | 4,804 | 151 | 281 | 253 | 3.1 |
| Mumps virus | 4,780 | 4,929 | 142 | 214 | 204 | 2.9 |
| Measles virus | 4,931 | 5,157 | 158 | 257 | 244 | 3.2 |
| Zaire virus | 4,861 | 5,439 | 141 | 212 | 196 | 2.9 |
| Hendra virus | 5,204 | 6,002 | 126 | 219 | 203 | 2.4 |
| SARS-CoV | 9,759 | 14,131 | 299 | 790 | 699 | 3.0 |
| HHV-4 | 32,670 | 34,497 | 1,899 | 7,050 | 3433 | 5.8 |
| HHV-6 | 42,426 | 44,048 | 1,242 | 3,954 | 2236 | 2.9 |
| Variola virus | 53,044 | 53,107 | 1,638 | 2,760 | 1916 | 3.0 |
| HHV-5 | 63,216 | 64,140 | 3,176 | 16,745 | 6030 | 5.0 |
| Allc | 284,918 | 298,232 | 10,863 | 31,737 | ||
Human proteome formed by 36,103 proteins and 15,697,964 occurrences of 10,431,975 unique 7-mers. Column number refers to: (1) unique 7-mers in the viral proteome; (2) total number of 7-mers in the viral proteome (including multiple occurrences); (3) unique viral 7-mers occurring in the human proteome; (4) viral overlap occurrences in the human proteome (including multiple occurrences); (5) number of human proteins involved in overlap; (6) % of unique viral 7-mers which occur in the human proteome (i.e. 100 × column 3/column 1).
Abbreviations as in Table 1.
The results of linear regression analysis between columns 1 and 3, and 1 and 4 are: column 3 = 0.042176 × column 1 − 36.723 (r = 0.95637); column 4 = 0.17329 × column 1 − 410.74 (r = 0.84397).
Obtained by combining all 30 viral proteomes into one viral proteome, and then computing the overlap with the entire human proteome.