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. 2009 Apr 23;27(29):3912–3920. doi: 10.1016/j.vaccine.2009.04.001

Table 1.

Predicted CTL epitopes for SARS-CoV nucleocapsid protein.

Name Position Sequence SYFPEITHIa BIMASb BL50 (μM)c
N-113 113–122 YLGTGPEASL 98.3 26 25.7 ± 11.2
N-159 159–168 VLQLPQGTTL 309.1 29 235.3 ± 68.7
N-222 222–231 LLLLDRLNQL 69.6 24 52.6 ± 10.5
N-223 223–231 LLLDRLNQL 98.3 20 46.1 ± 4.9
N-227 227–235 RLNQLESKV 36.3 23 165.1 ± 36.6
N-317 317–325 GMSRIGMEV 1267.1 30 72.8 ± 37.7
N-331 331–340 WLTYHGAIKL 50.2 21 90.4 ± 39.2
N-352 352–360 ILLNKHIDA 31.2 19 140.5 ± 44.6
a

Peptide binding scores to HLA-A2.1 were determined by the SYFPEITHI database [16] at http://www.syfpeithi.de/.

b

Peptide binding scores to HLA-A2.1 were determined by the BIMAS database [17] at http://www-bimas.cit.nih.gov/molbio/hla_bind/.

c

Data of peptide binding assays are shown as BL50, indicating a concentration of each peptide that yields the half-maximal MFI of T2 cells pulsed with a control peptide, NS3-1585. Data are given as mean values ± SD of three independent experiments.