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Binding constant (log K) of 5b and CQ with heme and DNA.
| Compound | Monomeric heme, log K ± σ |
μ-oxoheme, log K ± σ | CT DNA, log K | pUC18 DNA, log K | |
|---|---|---|---|---|---|
| pH 5.6 | pH 7.4 | pH 5.8 | |||
| 5ba | 4.58 ± 0.042 | 4.96 ± 0.029 | 5.72 ± 0.025 | 5.76 | 5.73 |
| CQ | 4.65 ± 0.052 | 5.15 ± 0.176 | 5.58 ± 0.006 | nd | nd |
| Stoichiometry | 1:1 | 1:1 | nd | ||
Calculated from HypSpec software.
