Table 1.

| Comp. | R1 | R2 | R3 | R4 | R5 | X | Mol. Formula | Mol. Wt. | m.p. | Rf value (CHCl3) | Yield % |
|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | NH2 | H | H | H | H | C O | C20H15N3O4S | 393.42 | 116–-118 | 0.33 | 70.9 |
| 2 | H | H | H | H | H | C O | C20H14N2O4S | 378.40 | 93–95 | 0.49 | 43.9 |
| 3 | H | H | NH2 | H | H | C O | C20H15N3O4S | 393.42 | 212–-214 | 0.43 | 99.0 |
| 4 | Cl | H | H | H | H | C O | C20H13ClN2O4S | 412.85 | 128–-130 | 0.48 | 37.5 |
| 5 | H | H | Cl | H | H | C O | C20H13ClN2O4S | 412.85 | 65–-67 | 0.44 | 63.5 |
| 6 | H | OH | H | H | H | C O | C20H14N2O5S | 394.40 | 98–-100 | 0.41 | 101.6 |
| 7 | OH | H | OH | H | H | C O | C20H14N2O6S | 410.40 | 163–-165 | 0.38 | 70.6 |
| 8 | H | H | OCH3 | H | H | C O | C21H16N2O5S | 408.43 | 90–92 | 0.36 | 60.9 |
| 9 | H | H | NO2 | H | H | C O | C20H13N3O6S | 423.40 | 92–-94 | 0.34 | 46.3 |
| 10 | CH3 | H | H | H | H | C O | C21H16N2O4S | 392.43 | 70–72 | 0.35 | 37.0 |
| 11 | H | H | CH3 | H | H | C O | C21H16N2O4S | 392.43 | 95–97 | 0.45 | 28.1 |
| 16 | OH | H | H | H | H | C O | C20H14N2O5S | 394.40 | 78–-80 | 0.77 | 60.0 |
| 20 | H | H | CH3 | H | H | SO2 | C20H16N2O5S2 | 428.48 | 156–-158 | 0.40 | 35.8 |
| R | |||||||||||
| 12 | –CH CH–CH3 | C17H14N2O4S | 342.37 | 112–-114 | 0.82 | 30.2 | |||||
| 13 | –CH CH2 | C16H12N2O4S | 328.34 | 100–102 | 0.56 | 32.8 | |||||
| 14 | –C(CH3) = CH2 | C17H14N2O4S | 342.37 | 102–-104 | 0.43 | 33.5 | |||||
| 15 | C19H13N3O4S | 379.39 | 110–-112 | 0.96 | 44.0 | ||||||
| 17 | –CH2–(CH2)2–CH3 | C18H18N2O4S | 358.41 | 107–-109 | 0.42* | 33.8 | |||||
| 18 | –CH2–(CH2)6–CH CH–(CH2)7–CH3 | C31H42N2O4S | 538.74 | 109–111 | 0.75 | 31.7 | |||||
| 19 | –CH2–(CH2)13–CH3 | C29H40N2O4S | 512.70 | 115–117 | 0.83* | 61.3 | |||||
*TLC mobile phase – Benzene.