Table 5.

Protection against BoHV-1 challenge of calves vaccinated with Gold standard vaccines of different quality.

Vaccinea	n	ELISA Ab titer at 60 dpv	Bovines						Guinea pig
			Virus shedding			Clinical signs			ELISA ab titer at 30 dpv
			Peak of infectious virus titer (TCID50/ml)	Duration of virus shedding (days)	AUCib	Rhinitys severity	Duration (days)	AUCsc
1	6	3.76Ad	2.4C	2.3B	6.2C	1.5B	11A	15.7A	3.1A
2	6	2.6B	5.0B	6.7A	22.2B	1.9AB	12A	20. 6A	2.7A
Placebo	9	0.3C	6.9A	7.1A	34.7A	2.5A	14A	33.8B	0.3B

^aVaccines previously classified by the guinea pig model and the host species as “very satisfactory” (1) and “satisfactory” (2).

^bAUCi area under the curve obtained by plotting the virus titer shed during 14 days after challenge.

^cAUCs area under the curve obtained by plotting the severity of the disease registered during 14 days after challenge.

^dMean in the same column with different uppercase letters, indicates significant differences as determined by one-way ANOVA, p < 0.05.