Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
Inhibition of orthopoxvirus replication by pyrazolo-pyrimidine nucleosides.
| Com. | EC50 (μM) |
Toxicity CC50 (μM) Neutral red uptake | |||
|---|---|---|---|---|---|
| Vacciniad CPE | Vacciniad PR | Cowpox CPE | Cowpox PR | ||
| Cidofovir | 3.2 | 20 | 7.1 | 32 | >317 |
| 161 | 1.7 | 6.9 | 0.3 | 5.6 | >286 |
| 162 | 20 | 11 | 1.8 | 9.0 | >292 |
Note: CPE-reduce viral cytopathogenicity, PR-plaque formation.
