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Cytotoxic activity as IC50 (μM) of pyrazolone derivatives against tested cell lines.
| Com. |
In vitro cytotoxicity IC50 (μM) |
||
|---|---|---|---|
| MCF-7 | MDA-MB-361 | MDA-MB-453 | |
| 73 | – | 9.98 | 10.24 |
| 74 | – | 12.17 | 8.75 |
| 75 | 60.72 | – | – |
| 76 | 43.41 | – | – |
| 77 | 30.68 | – | – |
| 78 | 37.22 | – | – |
| 79 | 54.23 | – | – |
| 80 | 44.99 | – | – |
| 81 | 44.99 | – | – |
