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Antidepressant effect of compounds 104 and 105.
| Com. | Forced swimming test |
Tail suspension test |
||
|---|---|---|---|---|
| Duration of immobility (s) | Change in immobility (%) | Duration of immobility (s) | Change in immobility (%) | |
| Control | 203.3 | – | 185.8 | – |
| Imipramine | 94.0 | −53.8 | 109.0 | −41.3 |
| 104 | 97.7 | −51.9 | 114.3 | −38.4 |
| 105 | 129.5 | −36.3 | 111.0 | −40.2 |
