Table 9.

Inhibition ratio of 108 and 109 on Alzheimer’s enzymes.

Com.	AChE IC50 (nM)	BChE inhibition % (10−3 M)	MAO-A inhibition %	MAO-B IC50 (nM)
Donepezil	29	94.1	–	–
108	57	96.3	42.3	–
109	–	35.3	38.1	49