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. Author manuscript; available in PMC: 2020 Nov 15.
Published in final edited form as: Int J Cancer. 2019 Aug 20;146(10):2680–2693. doi: 10.1002/ijc.32576

Figure 3. Forest plot of hazard ratios for dichotomous hypertension and antihypertensive treatment.

Figure 3

AC – adenocarcinoma; CNS – central nervous system; HCC – hepatocellular carcinoma; SCC – squamous cell carcinoma; SmallCC – small cell carcinoma; Hypertension – defined as systolic blood pressure (SBP) ≥140 mmHg, or diastolic BP (DBP) ≥90 mmHg at the BP measurement visit, or self-reported history of hypertension; Antihypertensive treatment status – either self-reported or no treatment assumed if there was self-reported absence of diagnosis of hypertension; Cases – numbers per group (hypertension / no hypertension & treated / untreated hypertension); Vertical order – determined by the hazard ratio estimates for SBP of the main anatomical locations (dot symbols), each followed by the relevant specific locations or morphologies marked with ^ (+ symbols) (as per Figure 2) (other locations, not included in those specified, are shown last); Hazard ratios – estimates (95% confidence intervals) (per 10 mmHg higher BP) were derived from Cox proportional hazards models, stratified by study centre and age at recruitment (5-year categories) and adjusted for potential confounders and risk factors listed in Supplementary Table 2. For cervical AC (n=37): HR=1.23 (0.58-2.06) and for other morphology in the cervix (non-SCC and non-AC) (n=41): HR=1.82 (0.92-3.63) (considered only in the main analyses and omitted from the plot to avoid the larger confidence intervals dominating the plot); * p<0.05, ** p<0.005.