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. 2020 Jun 18;9(7):20. doi: 10.1167/tvst.9.7.20

Table 1.

Details for the Materials Injected into Abca4/ Mice

Injection Material Details Dose (Total Genome Copies Per Eye) Abbreviated Name
AAV diluent: PBS with 0.001% PF68 Not applicable Sham
GRK1.GFP.pA: GRK1 promoter driving GFP expression 2E+10 GFP
GRK1.ABC: GRK1 promoter with the 5′ portion of ABCA4 coding sequence 2E+10 5′ vector high dose
2E+09 5′ vector low dose
CA4.WPRE.pA: 3′ portion of ABCA4 coding sequence with WPRE and polyA signal 1E+10 3′ vector
GRK1.ABC + CA4.WPRE.pA: 1:1 mix of 5′ and 3′ vectors 2E+10 Dual vector high dose
2E+09 Dual vector low dose

PF68, pluronic PF-68.