Table 1. Baseline characteristics according to prior fracture status.
| Characteristic | No fracture | Any high-trauma fracture | Any low-trauma fracture |
|---|---|---|---|
| N=64,626 | N=858 | N=14,758 | |
| Age (years) | 63.7 ± 11.0 | 65.1 ± 11.4 *** | 67.2 ± 11.4 *** |
| Sex (female) | 58,540 (90.6) | 661 (77.0) *** | 12874 (87.2) *** |
| BMI (kg/m2) | 27.3 ± 8.4 | 27.4 ± 5.4 | 27.2 ± 6.8 |
| Parental hip fracture | 4850 (7.5) | 75 (8.7) | 1171 (7.9) |
| Smoking | 5954 (9.2) | 99 (11.5) * | 1873 (12.7) * |
| Glucocorticoid use | 3776 (5.8) | 48 (5.6) | 593 (4.0) |
| Rheumatoid arthritis | 1900 (2.9) | 29 (3.4) | 370 (2.5) |
| Secondary osteoporosis | 9410 (14.6) | 127 (14.8) | 2008 (13.6) |
| High alcohol use | 251 (0.4) | 15 (1.7) *** | 212 (1.4) |
| Femoral neck T-score | -1.3 ± 1.0 | -1.6 ± 1.0 *** | -1.7 ± 1.0 ** |
| Residency (rural vs urban) | 20,528 (31.8) | 358 (41.7) *** | 5040 (34.2) *** |
| Income (lower vs higher) | 21,794 (33.7) | 313 (36.5) | 5883 (39.9) * |
| Anti-osteoporosis medication use | 18,665 (28.9) | 274 (31.9) | 5292 (35.9) * |
| Breast cancer diagnosis | 4706 (7.3) | 38 (4.4) ** | 703 (4.8) |
| Aromatase inhibitor use | 2950 (4.6) | 25 (2.9) * | 364 (2.5) |
| Comorbidity score | 4.7 ± 2.7 | 5.7 ± 3.0 *** | 5.6 ± 2.9 |
Data expressed as mean (SD) or N (percent). BMI, body mass index. * P < 0.05, ** P < 0.01, *** P < 0.001; No fracture vs Trauma, Trauma vs No-trauma