Table 4. Adjusted hazard ratios (HR) with 95% confidence intervals (CI) for incident fracture according to prior fracture status.
| Incident fracture | Prior fracture | High-trauma fracture | Low-trauma fracture | High-trauma fracture | |||
|---|---|---|---|---|---|---|---|
| Referent: No fracture | Referent: No fracture | Referent: Low-trauma fracture | |||||
| HR (95%CI) | P | HR (95%CI) | P | HR (95%CI) | P | ||
| Major osteoporotic fracture | Any fracture |
1.31
(1.08-1.59) |
0.005 |
1.55
(1.47-1.63) |
<0.001 | 0.85 (0.70-1.03) |
0.093 |
| Major osteoporotic fracture | Hip |
1.38
(1.01-1.88) |
0.043 |
1.18
(1.04-1.35) |
0.010 | 1.16 (0.83-1.63) |
0.372 |
| Major osteoporotic fracture | Major osteoporotic fracture |
1.48
(1.17-1.88) |
<0.001 |
1.57
(1.49-1.66) |
<0.001 | 0.94 (0.74-1.19) |
0.626 |
| Hip fracture | Any fracture | 1.35 (0.99-1.84) |
0.062 |
1.34
(1.23-1.47) |
<0.001 | 1.00 (0.73-1.37) |
0.988 |
| Any fracture | Any fracture |
1.39
(1.18-1.64) |
<0.001 |
1.61
(1.54-1.68) |
<0.001 | 0.87 (0.73-1.02) |
0.090 |
Results from Cox regression model. Adjusted for age, sex, body mass index, parental hip fracture, smoking, glucocorticoid use, rheumatoid arthritis, secondary causes of osteoporosis, high alcohol intake, femur neck T-score, rural vs urban residency, lower vs higher income, osteoporosis treatment, diagnosed breast cancer, aromatase inhibitor use, Johns Hopkins ADG comorbidity score. Estimates in bold-face font are statistically significant at α = .05.