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. Author manuscript; available in PMC: 2020 Aug 7.
Published in final edited form as: Blood. 2018 Jun 14;132(7):694–706. doi: 10.1182/blood-2017-10-810739

Figure 2. MPN and B-cell malignancy coexist in Stat1 −/− mice.

Figure 2

(A) Representative smears (BM, PB, original magnification: 40X; hematoxylin and eosin stainings) and photographs of spleens and livers. (B) Presence of Gr1+Mac1+ cells of wt and MPN+ Statl −/− animals (FACS; BM, spleen). One representative example per genotype is shown in (A) and (B). (C) FACS analysis of Gr1+Mac1+ and CD19+ (spleen). One representative example per experimental group is shown. (D) Absolute cell numbers of CD19+ cells in BMs and spleens of transplanted mice (n = 3 each). Data represent means ± SD; BM cntrl vs BM Statl−/− recipient. **P < .01; ***P < .001). (E) Representative photographs of spleens of control (phosphate-buffered saline injected) and BMT mice.