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. Author manuscript; available in PMC: 2020 Nov 1.
Published in final edited form as: Nat Cancer. 2020 May 22;1(5):546–561. doi: 10.1038/s43018-020-0066-y

Extended Data Fig. 8. Pan-TCGA association between a signature of T cell differentiation skewing and patient outcomes.

Extended Data Fig. 8

(a) Forest plot showing the relationship between the TL-DS signature and survival across TCGA cohorts (n=6853 patients). HRs and FDR adjusted p-values are from univariable Cox regression analysis. (b) Relationship between the TL-DS signature and survival, corrected for T cell infiltration, TMB and stage, in cohorts from (b) in which the signature predicted survival (9 cohorts, n=2418 patients). HRs and p-values are from multivariable Cox regression analysis. Cohorts in which the relationship was significant are shown.