Table 2. Model parameters and their base values for the model.
No. | Parameter (unit) | Symbol | Base value |
---|---|---|---|
R a distribution | |||
1 | Minimum value (Ω cm) | R a−soma | 120 |
2 | Maximum value (Ω cm) | R a−end | 70 |
3 | Half-maximal point of sigmoid (μm) | R a−HMP | 300 |
4 | Slope of sigmoid (μm) | R a−slope | 50 |
R m distribution | |||
5 | Minimum value (kΩ/cm2) | R m−soma | 125 |
6 | Maximum value (kΩ/cm2) | R m−end | 850 |
7 | Half-maximal point of sigmoid (μm) | R m−HMP | 300 |
8 | Slope of sigmoid (μm) | R m−slope | 50 |
Properties of spiking conductances | |||
9 | Maximal conductance of fast sodium channel (mS/cm2) | ḡ Na | 16 |
10 | Maximal conductance of delayed rectifier potassium channel (mS/cm2) | ḡ KDR | 10 |
h channel properties | |||
11 | Maximal somatic conductance (μS/cm2) | ḡ h | 25 |
12 | Fold increase | ḡ h−fold | 12 |
13 | Half-maximal point of sigmoid (μm) | ḡ h−HMP | 320 |
14 | Slope of sigmoid (μm) | ḡ h−slope | 50 |
T-type Ca2+ channel properties | |||
15 | Maximal somatic conductance (μS/cm2) | ḡ CaT | 80 |
16 | Fold increase | ḡ CaT−fold | 30 |
17 | Half-maximal point of sigmoid (μS/cm2) | ḡ CaT−HMP | 350 |
18 | Slope of sigmoid (μm) | ḡ CaT_slope | 50 |
A-type K+ channel properties | |||
19 | Maximal somatic conductance (mS/cm2) | ḡ KA | 3.1 |
20 | Fold increase per 100 μm | ḡ KA−fold | 8 |
These parameter values are identical to those described in Basak and Narayanan (2018b)
HMP half-maximal point