Table 2. FLG genotyping results for patients of white European ethnicity.
Cases n (%) | Controls n (%) | |
---|---|---|
Co-morbid atopic disease | 22 (44.9) | Undetermined |
| ||
FLG wild type genotype | 38 (77.6) | 88 (88.0) |
FLG heterozygote genotype | 10 (20.4) | 12 (12.0) |
FLG homozygote or compound heterozygote | 0 | 0 |
Incomplete genotyping data0 | 1 (2.0) | 0 |
| ||
Total | 49 (100.0) | 100 (100.0) |
| ||
Chi2 analysis | p=0.16 | |
Odds ratio (95% CI) | 1.02 (0.77 to 4.85) |
Cases with Fitzpatrick skin type of IV-V were excluded from the genetic analysis because FLG loss-of-function mutations remain ill-defined in these ethnic groups.