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. Author manuscript; available in PMC: 2020 Sep 2.
Published in final edited form as: Cell Rep. 2019 Dec 17;29(12):3946–3957.e5. doi: 10.1016/j.celrep.2019.11.030

Figure 4. Ag Availability Tunes the Quality-Quantity Trade-Off in the GCR.

Figure 4

(A-D) GC characteristics: (A) size; (B) plasma cell output; (C) affinity of GC B cells; and (D) cumulative Ab output at week 4 upon passive administration of exogenous Abs with intermediate (left column) and high (right column) affinity for Ag under low (η = 10, blue) and high (η = 14, magenta) Ag availability regimes. Shaded regions and error bars represent SEMs. See also Figure S3.