Fig. 3.

Inflammatory reaction in control defects filled with CFG (14 days postoperatively). First and second rows show representative examples from two different animals. micro-CT imaging showed loss of the trabecular structure and bone resorption (A, E). Upon sectioning the bone loss was confirmed, and a reaction of the surrounding area with inflammation was visible to the naked eye (B, F). HE staining showed a focal reaction (C, G) with recruitment of neutrophil granulocytes with loss of architecture and bone structure (D, H). CFG, commercial fibrin glue; HE, hematoxylin and eosin. Color images available online at www.liebertpub.com/tec