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Mechanism of EE-TP action. Plasma thymidine and 2’-deoxyuridine enter the erythrocyte via nucleoside transports located in the cell membrane, where the encapsulated TP catalyses their metabolism to thymine and uracil. The products then exit the cell into the blood plasma where they enter the normal metabolic pathways. TP: thymidine phosphorylase; EE-TP: erythrocyte encapsulated thymidine phosphorylase
