| FIP200 |
Conditional deletion |
Thinner SVZ, reduced olfactory bulb, decreased NSC proliferation |
[23] |
| Ambra1 |
Ambra1+/- Isolated NSCs |
Reduced proliferation, increased cell death |
[24] |
| Ambra1 |
Ambra1 -/- Ambra1 -/+ |
Reduced neuronal markers, smaller neurospheres, lesser neuronal differentiation (as seen by which markers) |
[25] |
| Beclin 1 |
Beclin1+/- |
Reduced proliferation, increased cell death, smaller neurospheres |
[24] |
| Atg5 |
Atg5 -/- |
Reduced neuronal differentiation |
[25] |
| Atg5 |
In utero electroporation of shRNA |
Decreased neural differentiation, aberrant morphology of cortical neurons |
[26] |
| Atg5 |
Atg5 -/- NSCs |
Delayed neuronal differentiation, transient reduction of spine density |
[31] |
| Eva1a1 |
Eva1a1 -/- NSCs |
Reduced self-renewal, reduced differentiation |
[27] |
