Table 1.
Baseline characteristics
|
Patients with intracranial vascular imaging, N=1368 |
p value | |||
|---|---|---|---|---|
| Intracranial stenosis, n=241* | No intracranial stenosis, n=1108 | |||
| Age, years | 76·0 (11·9) | 67·7 (13·8) | <0·0001 | |
| Sex | .. | .. | 0·40 | |
| Male | 127 (52·7%) | 558 (50·4%) | .. | |
| Female | 114 (47·3%) | 550 (69·6%) | .. | |
| White ethnicity | 229 (95·0%) | 1045 (94·3%) | 0·56 | |
| Hypertension | 168 (69·7%) | 572 (51·6%) | <0·0001 | |
| Diabetes | 42 (17·4%) | 134 (12·1%) | <0·0001 | |
| Hyperlipidaemia | 103 (42·7%) | 355 (32·0%) | <0·0001 | |
| Current smoker | 26 (10·8%) | 165 (14·9%) | 0·090 | |
| Atrial fibrillation | 52 (21·6%) | 145 (13·1%) | 0·0010 | |
| Any vascular disease† | 105 (43·6%) | 259 (23·4%) | <0·0001 | |
| History of stroke or transient ischaemic attack | 58 (24·1%) | 143 (12·9%) | <0·0001 | |
| Peripheral vascular disease | 24 (10·0%) | 36 (3·2%) | <0·0001 | |
| Ischaemic heart disease | 54 (22·4%) | 120 (10·8%) | <0·0001 | |
| Event type | .. | .. | 0·22 | |
| Transient ischaemic attack | 146 (60·6%) | 735 (66·3%) | .. | |
| Minor ischaemic stroke | 95 (39·4%) | 373 (33·7%) | .. | |
| TOAST classification | .. | .. | <0·0001 | |
| Cardioembolic | 35 (14·5%) | 172 (15·5%) | .. | |
| Atherosclerotic | 95 (39·4%) | 78 (7·0%) | .. | |
| Undetermined | 47 (19·5%) | 494 (44·6%) | .. | |
| Lacunar | 11 (4·6%) | 120 (10·8%) | .. | |
| Multiple, unknown, or other | 53 (22·0%) | 244 (22·1%) | .. | |
| Vascular territory | .. | .. | 0·12 | |
| Carotid | 129 (53·5%) | 580 (52·4%) | .. | |
| Vertebrobasilar | 94 (39·0%) | 408 (36·8%) | .. | |
| Uncertain or both | 18 (7·5%) | 120 (10·8%) | .. | |
| Imaging method | .. | .. | 0·039 | |
| MR angiography | 188 (78·0%) | 829 (74·8%) | .. | |
| CT angiography | 49 (20·3%) | 202 (18·2%) | .. | |
| Transcranial Doppler | 4 (1·7%) | 77 (7·0%) | .. | |
TOAST=Trial of Org 10172 in Acute Stroke Treatment.
*
Excluding patients with intracranial vessel occlusion (n=19).
†
Vascular disease includes ischaemic stroke, transient ischaemic attack, peripheral vascular disease, or ischaemic heart disease.