Table 2.

Predictors of any symptomatic or asymptomatic 50–99% intracranial stenosis

		Unadjusted risk predictors odds ratio (95% CI)	p value	Age-adjusted risk predictors odds ratio (95% CI)	p value	Multivariable risk predictors odds ratio (95% CI)	p value
Age, per 10 years		1·71 (1·51–1·94)	<0·0001	..	..	1·60 (1·39–1·83)	<0·0001
Male sex		1·10 (0·83–1·45)	0·51	1·31 (0·98–1·76)	0·066	1·17 (0·87–1·58)	0·31
Hypertension		2·16 (1·60–2·91)	<0·0001	1·58 (1·15–2·15)	0·0040	1·34 (0·96–1·87)	0·081
Diabetes		1·53 (1·05–2·24)	0·027	1·48 (1·00–2·18)	0·050	1·19 (0·79–1·81)	0·41
Hyperlipidaemia		1·58 (1·19–2·11)	0·0020	1·39 (1·03–1·86)	0·029	1·04 (0·76–1·44)	0·79
Atrial fibrillation		1·87 (1·32–2·66)	<0·0001	1·34 (0·93–1·93)	0·12	1·18 (0·81–1·71)	0·39
Any previous vascular disease*		2·53 (1·89–3·38)	<0·0001	1·83 (1·35–2·49)	<0·0001	..	..
Previous stroke or transient ischaemic attack		2·14 (1·52–3·02)	<0·0001	1·72 (1·21–2·46)	0·0030	1·64 (1·13–2·38)	0·0090
Peripheral vascular disease		3·29 (1·93–5·63)	<0·0001	2·49 (1·43–4·33)	0·0010	1·94 (1·09–3·45)	0·024
Ischaemic heart disease		2·38 (1·66–3·40)	<0·0001	1·68 (1·16–2·44)	0·0060	1·34 (0·90–1·99)	0·18
Event type
	Transient ischaemic attack	1·00 (ref)	..	1·00 (ref)	..	1·00 (ref)	..
	Minor ischaemic stroke	1·28 (0·96–1·71)	0·089	1·40 (1·04–1·88)	0·027	1·37 (1·01–1·87)	0·040

^*Vascular disease includes ischaemic stroke, transient ischaemic attack, peripheral vascular disease, or ischaemic heart disease.