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Synthetic strategy the assembly of TFF1 monomer and homodimer. TFF1 sequence highlighted in green represents the N-terminal fragment and in blue the C-terminal fragment used for native chemical ligation. Residues in bold highlight the ligation site. CVII (red) enables dimerisation. Disulfide connectivity is indicated with black lines. NMR structures used for this scheme: TFF1 monomer PDB: 1PS2; TFF1 homodimer PDB: 1HI7. Disulfide bonds are shown in orange.
