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. Author manuscript; available in PMC: 2020 Oct 16.
Published in final edited form as: Adv Healthc Mater. 2019 Oct 11;9(1):e1900775. doi: 10.1002/adhm.201900775

Table 2.

Summary of existing fiber patterning technologies for cTE with resultant scaffolds and their respective properties. Symbols: NE: not evaluated.

Fiber technology Architecture Fiber diameter Pore size / Porosity Mechanical properties Application Ref.
Solution electrospinning Aligned 269 ± 33 nm ≈1.5 μm 1.45 ± 0.20 MPa Young’s Modulus, 0.17 ± 0.05 MPa tensile strength Myocardium [168]
Solution electrospinning Aligned ≈2.5 μm ≈2 μm 87.9 ± 24.7 MPa Young’s Modulus Myocardium [169]
Solution electrospinning Aligned 1.53 ± 0.05 μm to 5.13 ± 0.19 μm 480 ± 85 μm2 to 980 ± 150 μm2 1.22 ± 0.07 MPa Young’s Modulus Myocardium [171]
Solution electrospinning Aligned Nanorange Microporosity 500 ± 31 kPa longitudinal tensile elastic modulus, 74 ± 15 kPa transverse tensile elastic modulus Myocardium [173]
Rotary jet spinning Aligned ≈425 nm NE ≈17.5 ± 6.6 MPa Young’s Modulus Myocardium [136]
Solution electrospinning Aligned tube 4.04 ± 0.25 μm Porosity: 78–81% 3 MPa radial tangent modulus, 4.1 MPa circumferential tangent modulus Valves [181]
Solution electrospinning Trilayered tubular ≈150–500 nm NE, porous middle layer Aligned parallel: 23.03 ± 2.00 MPa, aligned perpendicular: 5.26 ± 0.31 MPa, random 15,73 ± 2.55 MPa Vasculature [185]
Melt electrospinning Squared and rectangular 4–12 μm 150–300 μm 0.70 ± 0.15 to 2.05 ± 0.15 MPa tensile modulus Myocardium [117]
Melt electrospinning Hexagonal NE 250–800 μm 5–11 MPa modulus in x-direction; 1–2 MPa modulus in y-direction Myocardium [34]
Melt electrospinning Serpentine shaped 19.76 ± 1.54 μm 250 μm to 1 mm 3.07 ± 0.23 to 4.87 ± 0.094 MPa tensile modulus Valves [118]
Near-field electrospinning Aligned fibers 0.5–3 μm 5–100 μm NE Vasculature [128]
Wet spinning Aligned tubular NE 1–5 μm NE Vasculature [186]
Microfluidic spinning Mosaic fibers, aligned tubular scaffolds ≈50 μm, 1.5 mm tube diameter NE NE Myocardium, vasculature [163]
Microfluidic spinning/ textile technology Hallow and solid fibers, weaved scaffolds with rectangular pores 20 ± 14 μm to 210 ± 5 μm ≈ 200 ± 1000 μm 6.3 ± 0.4 Pa to 730 ± 15 Pa Youngs modulus measured by an atomic force microscope across three different materials Myocardium, vasculature [159]