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A) Confocal microscopy Z-axis projection of MSN-PEG-DBCO and Bac-MSN placed on 3D collagen gel. B,C) Confocal microscopy 3D panoramic view of collagen gels which contains HT1080 human fibrosarcoma cells embedded incubated with MSN-PEG-DBCO B) and Bac-MSN C), respectively. Green dots correspond to FITC-labeled MSN, red color corresponds to actin filaments and blue color correspond to cell nuclei.
