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. Author manuscript; available in PMC: 2020 Dec 17.
Published in final edited form as: Curr Med Chem. 2020 Jan 1;27(41):7112–7132. doi: 10.2174/0929867327666200625143035

Table 2. Amino acid sequence of different CCK2R targeting peptide analogs suitable for labelling with radiometals.

Peptide analog Amino acid sequence
DTPA-minigastrin DTPA-Leu-Glu-Glu-Glu-Glu-Glu-Ala-Tyr-Gly-Trp-Met-Asp-Phe-NH2
DOTA-sCCK8 DOTA-Asp-Tyr(SO3H)-Met-Gly-Trp-Met-Asp-Phe-NH2
DOTA-CCK DOTA-DAsp-Tyr-Nle-Gly-Trp-Nle-Asp-Phe-NH2
DTPA-CCK DTPA-DAsp-Tyr-Nle-Gly-Trp-Nle-Asp-Phe-NH2
DTPA-MG0 DTPA-DGlu-Glu-Glu-Glu-Glu-Glu-Ala-Tyr-Gly-Trp-Met-Asp-Phe-NH2
DOTA-MG0 DOTA-DGlu-Glu-Glu-Glu-Glu-Glu-Ala-Tyr-Gly-Trp-Met-Asp-Phe-NH2
DOTA-MG11 DOTA-DGlu-Ala-Tyr-Gly-Trp-Met-Asp-Phe-NH2
DOTA-G-CCK8 DOTA-Gly-Asp-Tyr-Met-Gly-Trp-Met-Asp-Phe-NH2
SA106 DOTA-DAsp-Phe(p-CH2SO3H)-HPG-Gly-Trp-HPG-Asp-Phe-NH2 *
Sargastrin DOTA-Gln-Gly-Pro-Trp-Leu-Glu-Glu-Glu-Glu-Glu-Ala-Tyr-Gly-Trp-Nle-Asp-Phe-NH2
APH070 DOTA-His-His-Glu-Ala-Tyr-Gly-Trp-Met-Asp-Phe-NH2
DOTA-cyclo-MG1 DOTA-cyclo[γ-D-Glu-Ala-Tyr-D-Lys]-Trp-Met-Asp-Phe-NH2
DOTA-cyclo-MG2 DOTA-cyclo[γ-D-Glu-Ala-Tyr-D-Lys]-Trp-Nle-Asp-Phe-NH2
MGD5 DOTA-Gly-Ser-Cys-(Glu-Ala-Tyr-Gly-Trp-Nle-Asp-Phe-NH2)2
DOTA-PP-F6 DOTA-DGln-DGln-DGln-Ala-Tyr-Gly-Trp-Met-Asp-Phe-NH2
DOTA-PP-F10 DOTA-DGln-DGln-DGln-DGln-DGln-DGln-Ala-Tyr-Gly-Trp-Met-Asp-Phe-NH2
DOTA-PP-F16 DOTA-DGln-DGlu-DGln-DGlu-DGln-DGlu-Ala-Tyr-Gly-Trp-Met-Asp-Phe-NH2
DOTA-PP-F11/CP04 DOTA-DGlu-DGlu-DGlu-DGlu-DGlu-DGlu-Ala-Tyr-Gly-Trp-Met-Asp-Phe-NH2
DOTA-PP-F11-L DOTA-Glu-Glu-Glu-Glu-Glu-Glu-Ala-Tyr-Gly-Trp-Met-Asp-Phe-NH2
DOTA-PP-F11N DOTA-DGlu-DGlu-DGlu-DGlu-DGlu-DGlu-Ala-Tyr-Gly-Trp-Nle-Asp-Phe-NH2
*

HPG = homopropargylglycine