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. 2021 Jan;29(1):39–49. doi: 10.1016/j.joca.2020.11.001

Table II.

40-meter Fast-Paced Walk Test (40-m FPWT) differences at baseline, and changes immediately after exercise therapy and education between participants with and without comorbidities


Baseline 40-m FPWT
Mean m/s (95% CI)
3 mo. 40-m FPWT
Mean m/s (95% CI)
Change 3 mo. 40-m FPWT
Mean m/s (95% CI)
No comorbidities, n = 12,128
1.56 (1.56–1.57)
1.69 (1.68–1.69)
0.12 (0.12–0.13)

Difference at baseline
Difference in change at 3 months

Mean m/s (95% CI)
Unadjusted mean m/s (95% CI)
Adjusted mean m/s (95% CI)
HT, n = 5,716 −0.12 (−0.13 to −0.11) −0.00 (−0.01 to 0.01) −0.00 (−0.01 to 0.01)
HT + DM, n = 729 −0.22 (−0.25 to −0.20) −0.00 (−0.03 to 0.01) 0.00 (−0.02 to 0.02)
HT + HD, n = 630 −0.17 (−0.19 to −0.14) −0.01 (−0.03 to 0.01) −0.01 (−0.03 to 0.01)
Resp, n = 558 −0.07 (−0.10 to −0.04) −0.01 (−0.03 to 0.01) −0.01 (−0.03 to 0.01)
HD, n = 551 −0.09 (−0.11 to −0.06) −0.01 (−0.03 to 0.01) −0.01 (−0.03 to 0.01)
Neu, n = 508 −0.05 (−0.08 to −0.03) 0.00 (−0.02 to 0.02) 0.00 (−0.02 to 0.02)
RA, n = 501 −0.06 (−0.09 to −0.04) 0.02 (−0.00 to 0.04) 0.02 (−0.00 to 0.04)
Ulcer, n = 447 −0.05 (−0.08 to −0.02) −0.01 (−0.03 to 0.01) −0.01 (−0.04 to 0.01)
Dep, n = 408 −0.09 (−0.12 to −0.06) 0.01 (−0.02 to 0.04) 0.01 (−0.02 to 0.04)
DM, n = 358 −0.15 (−0.18 to −0.11) −0,01 (−0.04 to 0.01) −0.01 (−0.04 to 0.01)
HT + Resp, n = 323 −0.20 (−0.24 to −0.17) −0.02 (−0.05 to 0.00) −0.03 (−0.05 to 0.00)
HT + RA, n = 275 −0.14 (−0.18 to −0.10) −0.03 (−0.06 to 0.00) −0.03 (−0.06 to 0.00)
HT + Neu, n = 274 −0.14 (−0.18 to −0.10) 0.01 (−0.02 to 0.04) 0.01 (−0.02 to 0.04)
HT + Ulcer, n = 254 −0.16 (−0.20 to −0.12) 0.02 (−0.01 to 0.05) 0.02 (−0.01 to 0.05)
Cancer, n = 234 −0.06 (−0.10 to −0.02) 0.01 (−0.02 to 0.04) 0.01 (−0.02 to 0.04)
HT + Dep, n = 203 −0.21 (−0.26 to −0.17) 0.01 (−0.02 to 0.05) 0.01 (−0.02 to 0.05)
HT + Cancer, n = 137 −0.16 (−0.22 to −0.11) −0.01 (−0.05 to 0.04) −0.01 (−0.05 to 0.04)
HT + HD + DM, n = 117 −0.26 (−0.32 to −0.20) 0.01 (−0.04 to 0.06) 0.01 (−0.04 to 0.06)
Anemia, n = 83 −0.04 (−0.11 to 0.03) −0.06 (-0.11 to -0.1) −0.06 (-0.11 to -0.01)
HT + Ren/Liv. n = 79 −0.09 (−0.16 to −0.02) −0.03 (−0.08 to 0.02) −0.03 (−0.08 to 0.02)
Number of comorbidities
1 comorbidity, n = 9,441 −0.10 (−0.11 to −0.9) −0.00 (−0.01 to 0.01) −0.00 (−0.01 to 0.01)
2 comorbidities, n = 3,838 −0.17 (−0.19 to −0.17) −0.01 (−0.01 to 0.00) −0.01 (−0.01 to 0.00)
3 comorbidities, n = 1,173 −0.23 (−0.25 to −0.21) −0.00 (−0.02 to 0.01) −0.00 (−0.02 to 0.01)
≥4 comorbidities, n = 392 −0.31 (−0.34 to −0.28) 0.01 (−0.02 to 0.03) 0.01 (−0.02 to 0.03)

n: Number, CI: Confidence interval. HT: Hypertension, DM: Diabetes mellitus one or 2, Resp: Respiratory disease, HD: Heart disease, Neu: Neurologic disease, RA: Rheumatoid arthritis, Dep: Depression, Ren/Liv: Renal and/or liver disease.

Adjusted for age, sex, BMI, educational level, not born in Denmark, civil status, physical activity, problems in other joints, use of analgesics, and number of bodily pain areas. Estimates in bold reflect statistical significance (P < 0.05).