Table 2.
Logistic regression model for primary outcome (favourable mRS 0-1). Logistic regression model fit was excellent (log-likelihood chi-squared test p<10-27; Hosmer & Lemeshow test p=0.305). The model explained 32% of the variance in functional outcome. WFNS = World Federation of Neurosurgical Societies; OR = Odds ratio; CI = confidence interval.
| p (overall effect) | OR | 95% CI | Contrast (vs reference) | P (contrast) | ||
|---|---|---|---|---|---|---|
| Age | 0.490 | 0.995 | 0.980 | 1.010 | ||
| Sex | 0.446 | 1.156 | 0.797 | 1.677 | Female (vs male) | |
| WFNS | <0.001 | 4.787 | 2.404 | 9.531 | WFNS 1 (vs 5) | <0.001 |
| Hydrocephalus | <0.001 | 2.004 | 1.386 | 2.897 | Absent (vs present) | <0.001 |
| Aneurysmal treatment | 0.005 | 1.817 | 1.194 | 2.763 | Coilingvs clipping | 0.014 |
| Nimodipine | 0.111 | 1.914 | 0.862 | 4.249 | Given vs not given | |
| Followup time | 0.121 | 1.007 | 0.998 | 1.015 | ||
| Centre | <0.001 | <0.001 | ||||
| Hypertension | 0.761 | 0.951 | 0.650 | 1.392 | Absent (vs present) | |
| Diabetes | 0.035 | 2.529 | 1.068 | 5.986 | Absent (vs present) | |
| Smoking (pack-years) | 0.441 | 1.003 | 0.995 | 1.012 | ||
| Hypercholesterolemia | 0.023 | 1.636 | 1.070 | 2.502 | Absent (vs present) | |
| Non-aSAH related disability | <0.001 | 5.536 | 2.984 | 10.271 | Absent (vs present) | |
| rs2000999 | 0.359 | 1.469 | 0.646 | 3.341 | GG vs AA | 0.154 |
| Fisher x HP | 0.013 | |||||
| Fisher | 0.009 | 4.105 | 1.428 | 11.806 | Low vs high Fisher in HP 1-1 | |
| HP | 0.011 | 2.602 | 1.381 | 4.904 | HP2-2 vs HP1-1 at high Fisher | 0.003 |