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. Author manuscript; available in PMC: 2021 Jan 17.
Published in final edited form as: Cancer Res. 2020 Oct 16;81(2):315–331. doi: 10.1158/0008-5472.CAN-20-1871

Figure 7. DZIP3 controls Cyclin D1-E2F axes.

Figure 7

(A) Schematic representation of DZIP3 controlling E2F downstream genes via Cyclin D1.

(B-C) A qRT-PCR analysis to evaluate the expressions of indicated genes from the total RNA of MCF7 control and DZIP3 stable knockdown cells. Data is presented as mean ± SE, n=3, *p<0.05, **p<0.005, ***p<0.0005.

(D) Western blot analysis of UM-UC3 control and DZIP3 stable knockdown tumor xenograft lysates probed with indicated antibodies

(E) Western blot analysis of MCF7 control and DZIP3 stable knockdown cell lysates probed with indicated antibodies

(F) Western blot analysis of HEK293 control and HA-DZIP3 transiently transfected cell lysates with indicated antibodies.

(G) Western blot analysis of MCF7 control and DZIP3 stable knockdown cells transfected with indicated plasmids and probed with indicated antibodies.

(H) Schematic presentation of work presented in this study.