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. Author manuscript; available in PMC: 2021 Jan 18.
Published in final edited form as: Hum Mol Genet. 2018 May 15;27(10):1809–1818. doi: 10.1093/hmg/ddy094

Table 1. Subjects used in the genome-wide association meta-analysis of IgM anti-PC.

Discovery phase Replication
TwinGene PIVUS MDC PRACSIS
Numbers
     All 1175   945   882   646
     Male   629   473   494   461
     Female   546   472   388   185
Age (years)
     All 74.2 ± 5.6 70.2 ± 0.2 60.8 ± 5.0 64.5 ± 9.5
     Male 73.9 ± 5.4 70.1 ± 0.1 60.7 ± 4.9 63.7 ± 9.6
     Female 74.5 ± 5.7 70.2 ± 0.2 60.9 ± 5.2 66.4 ± 8.9
IgM anti-PC (U/ml)
     All 42.7 (23.3−72.9) 42.4 (27.0−73.4) 48.0 (29.9−75.8) 34.9 (21.2−60.4)
     Male 42.6 (22.7−69.8) 39.1 (24.5−65.3) 48.0 (28.9−78.2) 35.1 (22.2−58.7)
     Female 42.8 (24.1−74.3) 47.9 (29.7−79.9) 48.0 (21.9−74.4) 34.0 (20.3−67.4)

Distribution of age is described as mean±SD; the raw values of IgM anti-PC are skewed distributed and presented by median (interquartile range, the 25th percentile– the 75th percentile).