Table 2. Details of the lead SNP rs35923643 from the meta-analysis on four studies.
SNP (Position) | Study | Info | β | SE | P-value | Phet |
---|---|---|---|---|---|---|
rs35923643 G/A | Meta | 0.189 | 0.029 | 4.34 × 10−11 | 0.159 | |
(Chr11: 123355391) | TwinGene | 0.999 | 0.153 | 0.050 | 0.002 | |
PIVUS | 0.980 | 0.263 | 0.054 | 1.18 × 10−6 | ||
MDC | 0.987 | 0.101 | 0.061 | 0.097 | ||
PRACSIS | 0.975 | 0.247 | 0.069 | 0.0004 |
SNP is presented with effect allele/alternative allele (chromosome number and position in human genome GRCh37/hg19). Info, imputation quality; β, effect size per SD of rank order normalized IgM anti-PC per allele; SE, standard error; Phet, P-value for heterogeneity.