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. Author manuscript; available in PMC: 2021 Jan 22.
Published in final edited form as: Mol Pharm. 2019 Apr 29;16(6):2494–2501. doi: 10.1021/acs.molpharmaceut.9b00086

Figure 3.

Figure 3

Normalized intensity traces of the liposome membranes. A: Intensity drop of the liposome membranes (N = 10) upon addition of dithionite. The mean intensity of the observed liposomes is shown in black with the standard deviations depicted in grey. The drop to half of the initial value is caused by the bleaching of the outer membrane leaflet by the dithionite. B: Liposome intensity (N = 3) stays stable throughout the entire experiment upon addition of buffer without dithionite, suggesting a negligible effect of photo bleaching. The insets show a representative liposome at the beginning of the measurement and after 2000 s. The scale bar shows 10 μm.