Table 5.
Loci associated with ambidexterity after a meta-analysis of 23andMe and UKBB data
| CHR | BP | SNP | Gene | EA | NEA | EAF | Z | ORa | P | Direction |
|---|---|---|---|---|---|---|---|---|---|---|
| 1 | 150317558 | rs782122127 | PRPF3 | D | I | 0.19 | –6.32 | 0.88 | 2.70 × 10–10 | ?– |
| 2 | 58196110 | rs2030237 | VRK2 | A | G | 0.58 | 5.84 | 1.04 | 5.29 × 10–9 | ++ |
| 2 | 104437850 | rs139630683 | AC0137271 | D | I | 0.45 | 5.85 | 1.05 | 4.88 × 10–9 | +? |
| 7 | 91899117 | rs2040498 | ANKIB1 | A | T | 0.65 | 6.21 | 1.06 | 5.42 × 10–10 | ++ |
| 8 | 77104817 | rs10113066 | RNU2–54P | T | G | 0.51 | 5.90 | 1.05 | 3.74 × 10–9 | ++ |
| 10 | 89722731 | rs36062478 | PTEN | T | C | 0.87 | –5.62 | 0.94 | 1.87 × 10–8 | – – |
| 12 | 49530132 | rs35554786 | TUBA1B | D | I | 0.24 | –6.05 | 0.93 | 1.49 × 10–9 | –? |
The direction of effects is shown in the following order: 23andMe and UKBB.
a
OR corresponds to that derived from the 23andMe results. Where the SNP is missing in a cohort, a question mark is indicated in the Direction column.