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. Author manuscript; available in PMC: 2021 Aug 1.
Published in final edited form as: Nat Chem Biol. 2020 Nov 16;17(2):187–195. doi: 10.1038/s41589-020-00694-2

Table 1.

Kinetic parameters for LptD peptides showing EX1 or EXX kinetics.

Peptide State R2 kop (min-1) Closed state t1/2 (min)
66-92 Apo 0.98 2.6-10-3
[2.6-10-3; 4.7-10-3]		 267
[147; 273]
+LPS 0.96 9.6-10-3
[6.2-10-3; 1.4-10-2]		 72.2
[50.0; 111]
93-104 Apo 0.91 2.9-10-3
[2.4-10-3; 4.2-10-3]		 238
[166; 290]
+LPS 0.89 6.2-10-3
[2.8-10-3; 1.0-10-2]		 112.4
[68.4; 251]
105-115 Apo 0.98 4.5-10-3
[3.4-10-3; 6.8-10-3]		 153
[103; 202]
+LPS 0.92 9.6-10-3
[4.4-10-3; 1.8-10-2]		 72.4
[38.6; 158]
105-118 Apo 0.98 3.1-10-3
[2.8-10-3; 4.0-10-3]		 226
[176; 251]
+LPS 0.97 7.4-10-3
[4.4-10-3; 1.1-10-2]		 72.4
[63.7; 158]
116-129 Apo 0.98 3.6-10-3
[2.2-10-3; 5.9-10-3]		 193
[116; 306]
+LPS 0.93 1.8-10-2
[1.1-10-2; 3.4-10-2]		 39.6
[19.9; 67.5]
119-129 Apo 0.98 3.3-10-3
[2.6-10-3; 5.8-10-3]		 213
[120; 268]
+LPS 0.96 1.1-10-2
[7.5-10-3; 1.7-10-2]		 61.1
[41.0; 92.3]
130-141 Apo 0.98 3.4-10-3
[2.6-10-3; 5.3-10-3]		 205
[130; 263]
+LPS 0.96 2.2-10-2
[1.4-10-2; 3.9-10-2]		 31.7
[18.9; 49.2]
171-179 Apo 0.97 1.4-10-3
[1.2-10-3; 3.2-10-3]		 497
[219; 570]
+LPS 0.89 8.0-10-3
[3.4-10-3; 1.4-10-2]		 86.8
[48.0; 202]