Table 2. Data collected at the pregnancy period of the S-PRESTO study.
PREGNANCY VISIT | Visit 1 (6-8wk) | Visit 2 (11-13 wk) | Visit 3 (18-21 wk) | Neurodevelopment visit 2 (24-26wk) | Visit 4 (27-28 wk) | Visit 5 (34-36 wk) |
---|---|---|---|---|---|---|
Ultrasound scan of pregnancy | Dating | Nuchal | Anomaly | - | Growth | Growth |
Interviews & self-administered questionnaires | ✓ | ✓ | ✓ | ✓ | ✓ | |
Measurements | ||||||
Height/weight/skinfolds | ✓ | ✓ | ✓ | ✓ | ✓ | |
Blood pressure | ✓ | ✓ | ✓ | |||
Cardiovascular assessment | ✓ | |||||
Retinal Photography | ✓ | ✓ | ✓ | |||
Accelerometry | ✓ | |||||
Biosample collection | ||||||
Blood | ✓ | ✓ | ✓ | (Fasting) | ✓ | |
OGTT (0, 30, 60, 90, 120 min) | ✓ | |||||
Urine | ✓ | ✓ | ✓ | ✓ | ✓ | |
Hair | ✓ | ✓ | ✓ | ✓ | ||
Buccal smear | ✓ | ✓ | ✓ | ✓ | ✓ | ✓ |
Stool | ✓ | ✓ | ||||
Dust | ✓ | |||||
Skin microbiome (Forehead, antecubital fossa) | ✓ | |||||
Epithelial swabs (Vaginal, vulva, rectal and breast) | ✓ | |||||
Socio-emotional assessment | ||||||
Online or hard-copy self-administered questionnaires 2 * | ✓ | ✓ | ✓ | |||
Tasks: Flanker - Emotional and Neutral, DCCS - Emotional and Neutral, Relational Binding – Neutral, Emotional Perception, CANTAB Spatial Working Memory, Adult Attachment Interview, Heart Rate | ✓ |
EPDS, BDI, STAI, Perceived Stress Scale, Multidimensional Scale of Perceived Support, Sufficiency of practical/emotional support, Other Sources of Social Support, Need to Belong, SES + income, Belief in a Dangerous World one item, Interpersonal Orientation Measure, Pittsburgh Sleep Questionnaire, Epworth Sleepiness Scale Questionnaire, Body Image Expectations and Dissatisfaction, Parental Bonding Instrument, Pregnancy Anxiety Scale (from Buss), Pregnancy Experiences Scale - Short version, Sleep Diary & Actiwatch, SF12, Loss Questionnaire
selected questionnaires are administered at each timepoint