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. 2020 Jul 28;29(20):3451–3463. doi: 10.1093/hmg/ddaa162

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© The Author(s) 2020. Published by Oxford University Press.

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted reuse, distribution, and reproduction in any medium, provided the original work is properly cited.

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Associations of metabolites with NASH-fibrosis variants in the Fenland and EPIC-Norfolk cohort. Metabolites are arranged by class and annotated whether they were obtained by untargeted or targeted methods. Beta (β) ± standard error (SE) per allele from linear regression models are presented, adjusted for age, sex and the first ten genetic principal components and after standardization of each metabolite. Only metabolites significantly associated with at least one variant of interest (Q < 0.05) are presented and marked in Red. MG, monoglyceride; PC, phosphatidylcholine; PI, phosphatidylinositol; SM, sphingomyelin.