Table 3. Absorbed Organ and Whole-Body Doses of 68Ga-THP-PSMA.
| Organ | Absorbed dose in patient: | Mean absorbed dose | Median absorbed dose | |||||||
|---|---|---|---|---|---|---|---|---|---|---|
| 1 | 2 | 3 | 4 | 5 | 6 | 7 | 8 | |||
| Adrenal glands | 7.00E–03 | 6.01E–03 | 7.36E–03 | 5.02E–03 | 4.85E–03 | 5.88E–03 | 5.57E–03 | 5.33E–03 | 5.88E–03 | 5.72E–03 |
| Brain | 1.14E–03 | 1.31E–03 | 2.15E–03 | 1.15E–03 | 1.20E–03 | 1.29E–03 | 9.35E–04 | 1.47E–03 | 1.33E–03 | 1.24E–03 |
| Gallbladder | 9.89E–03 | 7.54E–03 | 1.11E–02 | 7.24E–03 | 9.00E–03 | 8.42E–03 | 1.33E–02 | 7.03E–03 | 9.20E–03 | 8.71E–03 |
| Lower large intestine | 1.92E–02 | 8.42E–03 | 1.32E–02 | 6.63E–03 | 1.00E–02 | 9.39E–03 | 8.78E–03 | 1.01E–02 | 1.07E–02 | 9.71E–03 |
| Small intestine | 1.71E–02 | 1.44E–02 | 1.52E–02 | 2.25E–02 | 1.53E–02 | 1.53E–02 | 1.25E–02 | 1.36E–02 | 1.57E–02 | 1.53E–02 |
| Stomach | 9.89E–03 | 7.85E–03 | 1.17E–02 | 7.49E–03 | 7.84E–03 | 8.03E–03 | 7.70E–03 | 6.86E–03 | 8.42E–03 | 7.84E–03 |
| Upper large intestine | 8.04E–03 | 7.46E–03 | 9.96E–03 | 6.34E–03 | 7.36E–03 | 7.24E–03 | 6.48E–03 | 7.16E–03 | 7.50E–03 | 7.30E–03 |
| Heart | 1.04E–02 | 1.55E–02 | 2.80E–02 | 1.42E–02 | 1.55E–02 | 1.62E–02 | 1.50E–02 | 1.18E–02 | 1.58E–02 | 1.53E–02 |
| Kidneys | 7.26E–02 | 6.05E–02 | 9.07E–02 | 8.89E–02 | 9.13E–02 | 9.91E–02 | 5.87E–02 | 7.60E–02 | 7.97E–02 | 8.24E–02 |
| Liver | 1.83E–02 | 1.08E–02 | 1.79E–02 | 1.10E–02 | 1.52E–02 | 1.11E–02 | 1.05E–02 | 1.02E–02 | 1.31E–02 | 1.10E–02 |
| Lungs | 1.69E–02 | 1.18E–02 | 1.85E–02 | 1.53E–02 | 1.53E–02 | 1.56E–02 | 1.33E–02 | 1.09E–02 | 1.47E–02 | 1.53E–02 |
| Muscle | 5.15E–03 | 4.23E–03 | 5.69E–03 | 3.44E–03 | 4.50E–03 | 4.43E–03 | 4.25E–03 | 4.04E–03 | 4.47E–03 | 4.34E–03 |
| Pancreas | 9.41E–03 | 7.19E–03 | 1.46E–02 | 9.92E–03 | 1.30E–02 | 8.82E–03 | 8.26E–03 | 8.60E–03 | 9.98E–03 | 9.11E–03 |
| Red marrow | 9.86E–03 | 8.20E–03 | 1.05E–02 | 6.87E–03 | 7.58E–03 | 7.89E–03 | 7.57E–03 | 7.69E–03 | 8.27E–03 | 7.79E–03 |
| Osteogenic cells | 1.24E–02 | 1.07E–02 | 1.35E–02 | 8.52E–03 | 8.61E–03 | 1.00E–02 | 1.03E–02 | 9.52E–03 | 1.04E–02 | 1.02E–02 |
| Skin | 4.56E–03 | 4.13E–03 | 4.55E–03 | 2.93E–03 | 2.79E–03 | 3.65E–03 | 3.70E–03 | 3.56E–03 | 3.73E–03 | 3.68E–03 |
| Spleen | 1.56E–02 | 1.14E–02 | 1.63E–02 | 1.47E–02 | 1.38E–02 | 1.32E–02 | 1.05E–02 | 9.65E–03 | 1.31E–02 | 1.35E–02 |
| Testes | 1.12E–02 | 9.65E–03 | 1.08E–02 | 1.05E–02 | 1.28E–02 | 1.12E–02 | 1.03E–02 | 9.91E–03 | 1.08E–02 | 1.06E–02 |
| Thymus | 5.48E–03 | 4.91E–03 | 5.73E–03 | 3.56E–03 | 3.10E–03 | 4.31E–03 | 4.48E–03 | 4.02E–03 | 4.45E–03 | 4.39E–03 |
| Thyroid | 8.34E–03 | 8.07E–03 | 1.12E–02 | 6.05E–03 | 6.93E–03 | 6.27E–03 | 7.57E–03 | 7.38E–03 | 7.72E–03 | 7.47E–03 |
| Urinary bladder | 1.80E–01 | 1.78E–01 | 1.22E–01 | 1.51E–01 | 4.50E–01 | 2.67E–01 | 1.36E–01 | 3.36E–01 | 2.27E–01 | 1.79E–01 |
| Remainder | 7.97E–03 | 6.80E–03 | 8.33E–03 | 5.64E–03 | 6.28E–03 | 6.80E–03 | 6.35E–03 | 6.38E–03 | 6.82E–03 | 6.59E–03 |
| Effective dose (mSv/MBq) | 2.05E–02 | 1.71E–02 | 1.75E–02 | 1.60E–02 | 3.21E–02 | 2.25E–02 | 1.52E–02 | 2.49E–02 | 2.07E–02 | 1.90E–02 |