Extended Data Fig. 7. Effect of FluPol_A mutations at the FluPol_A-ANP32A interface on FluPol_A activity and interaction with huANP32A.

a, b, Effect of FluPol_A mutations at the FluPol_A-ANP32A interface on FluPol_A activity in viral minigenome assays on (a) and FluPol_AANP32A interaction (b). Data are presented as mean values ± s.e.m. n = 3 biologically independent samples from n = 3 independent experiments. Ordinary one-way ANOVA with Dunnett’s post hoc test for multiple comparisons. P < 0.05 is considered significant to reject the null hypothesis. Western blot analyses were repeated from n = 3 independent experiments with similar results. For gel source data, see Supplementary Fig. 2.